Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2016
  • Volume: 9
  • Issue: 12

In-vitro antibacterial activity of ethyl acetate extract of Sesbania grandiflora leaf against E. faecalis-A root canal threat

1Bachelor of Dental Surgery, Saveetha Dental College and Hospitals, Chennai, India

2Faculty of Pharmacology, Saveetha Dental College and Hospitals, Chennai, India

*Corresponding Author E-mail: anitharoy2015@gmail.com

Online published on 2 March, 2017.

Abstract

To evaluate the antibacterial activity of the Ethyl Acetate Extract of Sesbania grandiflora leaf against E. faecalis

Agar well diffusion assay as well as microbroth dilution assays were used for determination of antibacterial activity.

Different concentrations (200mg/mL, 400mg/mL and 800mg/mL) of the Ethyl Acetate extract of Sesbania grandiflora leaf showed dose dependant antibacterial activity and the MBC was found to be more than 400 mg/mL

This study suggests that the Ethyl acetate extract of S. grandiflora leaf contains promising antibacterial substances which is having activity against E. faecalis.

Keywords

Sebania grandiflora, E. faecalis, antibacterial activity, root canal failure