Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2016
  • Volume: 9
  • Issue: 7

Formulation, evaluation and release studies of Indomethacin Suppositories

  • Author:
  • Kalyani Dewangan1, Kushagra Nagori1, Mukesh Sharma1, Ajay Singh2, Sandhya Chandrakar1, Vandana Devi Sahu1, Garima Sharma1, Sujata Gupta1, Harsha Solanki1, Manisha Majumdar1, D. K. Tripathi1, Amit Alexander1, Ajazuddin1,
  • Total Page Count: 3
  • Page Number: 942 to 944

1Rungta College of Pharmaceutical Sciences and Research, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024

2GD Rungta College of Science and Technology, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: ajazuddin@rungta.ac.in

Online published on 15 October, 2016.

Abstract

Indomethacin suppositories were prepared by using water soluble bases. All the prepared suppositories were evaluated for various physical parameters like weight variation, hardness, Liquefaction time. In-vitro release study was performed USP type I apparatus (Basket type) using phosphate buffer pH 7.4 as dissolution media. The suppositories prepared were within permissible range of all physical parameters.

Keywords

Indomethacin, suppositories, Liquefaction time