A Review on Parkinson Disease

Parkinson's disease (PD), more commonly referred to as just Parkinson's, is a chronic degenerative condition primarily affecting the motor system of the central nervous system. Parkinson's disease (PD) is associated with a group of disorders known as motor system problems, which result in unexpected or erratic bodily developments. There is progressive development of both motor and non-motor symptoms, greatly affecting one’s overall quality of life. While there is no cure, various treatments have been developed to help manage the symptoms of PD. The clinical characteristics of PD with emphasis on those features that differentiate the disease from other parkinsonian disorders. Current treatment approaches focus on symptom management, as there is no cure for PD. The mainstay of therapy includes medications that aim to increase dopamine levels or mimic its action, such as levodopa and dopamine agonists. Surgical interventions like deep brain stimulation (DBS) are used in advanced cases. Despite these treatments, disease progression is inevitable, leading to increasing disability over time.