Research Journal of Science and Technology
  • Year: 2026
  • Volume: 18
  • Issue: 2

Antifungal, Antioxidant Activities and Spectroscopic characterization of N, N bis((3-methyl-1,2,4-triazole-5-thione)-1,3-methylidene) benzene and N, N bis((3-methyl-1,2,4-triazole-5-thione)-1,4-methylidene) benzene

Ph.D., Department of Basic Sciences, College of Dentistry, Damascus University, Syria

*Corresponding Author E-mail: maryam1.ashour@damascusuniversity.edu.sy

Abstract

N, N bis((3-methyl-1,2,4-triazole-5- thione)-1,3-methylidene) benzene and N, N bis((3-methyl-1,2,4-triazole-5-thione)-1,4-methylidene) benzene were synthesized and Characterization was done based on some physicochemical parameters; infrared and Uv-visible spectroscopic studies. The compounds synthesized were screened against some species of fungi such as Candida albican using the disc diffusion method .Antimicrobial screening of the synthesis’s compounds showed that, the process antimicrobial activities towards Candida albican and these results were compared with nystatin compound.

Keywords

Triazole, Methylidene, Candida albican, Antimicrobial activities, Antioxidant activities