Research Journal of Science and Technology

  • Year: 2017
  • Volume: 9
  • Issue: 4

Synthesis, Characterization and Antimicrobial Screening of NewCyclic Imides

1Research Scholar, School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India

2Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

*Corresponding Author E-mail: ykgbkbiet@rediffmail.com, ykgbkbiet@yahoo.com, ykgbkbiet123@gmail.com

Online published on 12 June, 2018.

Abstract

The Cyclic imides and their Derivatives have been attracted significantly more attention of organic and medicinal chemists due to their antimicrobial activities. The derivatives of six member cyclic imides were synthesized by the action of glutaric anhydride with different substituted aromatic amines to obtained 4-(Nphenylcarbamoyl) butanoic acid. These intermediates undergo ring closer with acetyl chloride furnished six member cyclic imides derivatives. All these derivatives were screened for their antimicrobial activities.

Keywords

Six member cyclic imides, glutarimide, 4-(N-phenylcarbamoyl) butanoic acid, N-Phenyl