Research Journal of Topical and Cosmetic Sciences

  • Year: 2020
  • Volume: 11
  • Issue: 1

Formulation and Evaluation of a Poly Herbal Anti-acne gel

1Department of Pharmacognosy, Seven Hills College of Pharmacy, Tirupati, Chitoor, AP, India

2Department of Pharmaceutical Chemistry, Seven Hills College of Pharmacy, Tirupati, Chitoor, AP, India

Abstract

Acne a common skin disease in adolescence is a bacterial skin disorder found in many teenagers. Herbal remedies are used in ancient system of medicine they have natural healing properties, they are used in various acute and chronic skin diseases, which include eczema, contact dermatitis, psoriasis, leprosy, and other major skin diseases.

The present research was undertaken to formulate a herbal gel containing Aloevera and turmeric extract. Aloevera and turmeric both these plants possess potential anti-inflammatory immunomodulatory and anti acne properties. Aloevera and turmeric contain antioxidants, scavenging of free radicals. Aloevera leaf was washed with water the gel was separated and collected from the leaf and stored in refrigerator for further studies. Turmeric (curcuma longa) was washed and dried in room temperature and size reduced to fine powder and stored in plastic container in desiccator for further studies. Gels were prepared with gelling agents and with incorporation of excipients and ingredients containing plant extracts.

Different gels were prepared with different concentrations of gelling agents. The gel was evaluated for different physicochemical properties which include colour, appearance, consistency, washability, pH, spreadibility, extrudability, viscosity, homogeneity, etc. The prepared gel did not show any phase separation it was stable and did not show any irritation on skin. The prepared gels were free from microbial contamination.

Both these plants have enhanced efficacy and potency and can be safe and effective against many diseases. These two plants have fewer side effects and toxicity and they have enhanced acne healing and other properties. Results shows prepared gel has promising effect on the anti acne process

Keywords

Anti acne, Aloevera, turmeric, polyherbal, gel