*Corresponding Author E-mail: nuwanthi.k@nsbm.ac.lk
Numerous variables, such as genetics, autoimmune diseases, hormone dysregulations, and environmental factors, might contribute to the development of Alopecia. Understanding the morphology of hair and its growth cycle is essential for comprehending the mechanisms underlying all types of alopecia and creating effective treatments for them. Androgenetic alopecia and Alopecia areata are the two most prevalent forms of Alopecia. Therefore, to treat these conditions, numerous synthetic drugs are being used. However, with the use of these synthetic drugs, it was found that they potentially cause severe adverse effects. Researchers have therefore investigated natural substances for their anti-alopecia properties, which have less or no side effects, while being cost-effective alternatives to chemically synthesized medications with economic benefits grounded in their sustainability, mainly due to their minimal clinical trial expenditures and patent protections. This review will provide a thorough and comprehensive understanding of the underlying causes of Alopecia, the prevailing treatment modalities, and the natural remedies used to treat Alopecia.
Alopecia, Minoxidil, Dihydrotestosterone (DHT), 5- alpha reductase, Anti-alopecia properties