Research Journal of Topical and Cosmetic Sciences
  • Year: 2025
  • Volume: 16
  • Issue: 2

Exploring Cannabidiol’s Therapeutic Potential in Skincare with Focus on Anti-Inflammation and Antioxidant Activity

  • Author:
  • Rohini C. Kolhe1,*, Aarti Shivareddy2
  • Total Page Count: 7
  • Published Online: Feb 27, 2026
  • Page Number: 142 to 148

1Department of Pharmacognosy, JSPM’S Rajarshi Shahu College of Pharmacy and Research, Tathawade, Pune

2Department of Pharmaceutics, JSPM’S Rajarshi Shahu College of Pharmacy and Research, Tathawade, Pune

*Corresponding Author E-mail: rohini.kolhe@gmail.com

Online Published on 27 February, 2026.

Abstract

Cannabidiol (CBD), a non-psychoactive compound sourced from the Cannabis sativa plant, has gained significant interest in the skincare industry for its therapeutic properties. Review highlights anti-inflammatory and antioxidant properties of Cannabidiol, focusing on its role in supporting skin health. Inflammation and oxidative stress are major factors in skin issues such as acne, eczema, psoriasis, and premature aging. By interacting with the endocannabinoid system, CBD helps regulate inflammatory processes, potentially alleviating these conditions. Additionally, its potent antioxidant activity aids in neutralizing free radicals, shielding the skin from environmental aggressors like UV rays and pollution. Recent studies emphasize CBD’s capacity to reduce pro-inflammatory cytokine production and combat oxidative stress, showcasing its potential in preventing and managing various skin conditions. Furthermore, its calming effects make it an ideal choice for sensitive skin, offering a natural alternative to conventional skincare ingredients. In summary, CBD shows great promise as a multifunctional ingredient in skincare, delivering both anti-inflammatory and antioxidant benefits. As interest in natural, effective skincare solutions continues to grow, further studies are needed to explore CBD’s mechanisms and evaluate its long-term impact in dermatology.

Keywords

Cannabidiol, Anti-Inflammatory, Antioxidant, Skincare, Endocannabinoid system