1 Graduated Pharmacist, P.S.G.V.P. Mandal's College of Pharmacy, Shahada, Maharashtra, 425409, India
This study focuses on addressing uneven melanin production, a prevalent dermatological and cosmetic issue responsible for skin hyperpigmentation. Kojic acid, a well-known natural depigmenting agent, was combined with herbal extracts such as niacinamide, licorice root extract, and aloe vera to develop a topical gel aimed at enhancing skin tone and regulating melanin synthesis. The formulation was designed to optimize skin compatibility and stability by incorporating suitable gelling agents, pH adjusters, and preservatives. The gel's characteristics were thoroughly evaluated through multiple parameters to ensure its suitability for topical application. Key evaluation criteria included clarity, physical appearance (color and consistency), homogeneity, pH measurement, spreadability, and drug content analysis. These assessments were conducted to confirm the uniformity, stability, ease of application, and effective delivery of active ingredients within the formulation. The comprehensive evaluation underscores the potential of this kojic acid-based gel combined with herbal extracts as an effective skin brightening and depigmentation product. The formulation holds promise for safe and efficient management of hyperpigmentation, making it a valuable addition to dermatological therapeutics and cosmetic skincare regimens.
Kojic acid, Licorice root, Aloe vera, Melanin production, Topical gel