Hepatoprotective Activity of Methanolic Extract of Rhyncosia Beddomei Baker Against Ethanol Induced Hepatotoxicity

In the present study, hepatoprotective activity of methanolic extract of Rhyncosia beddomei Baker leaves in ethanol induced hepatotoxicity was investigated. The activity was assessed against ethanol induced hepatotoxicity by measuring the levels of serum enzymes like SGOT SGPT and ALP, total proteins, total bilirubin, and triglycerides. Further, hepatic tissues were also subjected to histopathological studies. The extract showed significant hepatoprotective activity at 200 mg and 400 mg/kg b.w by decreasing the levels of SGPT, SGOT, ALP, total bilirubin, triglycerides and increasing the level of total proteins when compared to toxicant group. The histopathological studies further supported the activity. The results of the present study proved the hepatoprotective potential of methanolic extract of Rhyncosia beddomei Baker