This paper includes mainly the aero-thermodynamic issues related to hypersonic regimes of ISRO's space vehicles. The author's invited talk on hypersonic application of ISRO space vehicle programs presented in the Hypersonic Symposium in Hypersonic Technology at Ramaiah university is partly brought out in this paper. The critical issues like laminar-turbulent transition, thermal and chemical nonequilibrium, stagnation point heating, communication blackout and effect of wall catalyticity associated with hypersonic re-entry vehicles/space capsule are brought out with proper prospective. Different numerical fluid dynamics approaches suitable for hypersonic flows are discussed. Several aerothermal aspects of the SRE Space Re-entry Experiment conducted in the year 2007 are brought out. Two other important experiments like RLV HEX and ATV D02 with scramjet engines in 2016 are also covered. Many important ongoing activities related to hypersonic space vehicle programs like ORV (Orbital Launch Vehicle), HAVA (Hypersonic Air-breathing Vehicle with Airframe integrated), Chandrayaan-2 and Gaganyaan Crew Module are beyond the scope of this paper
ISRO, Orbital Launch Vehicle, Chandrayaan-2, Gaganyaan Crew Module
