Renal failure is one of the important causes of anaemia which warrants differential diagnosis for rational therapy. The aim of present study was to characterize the clinical indices associated with anaemia due to renal failure in dogs. A total of 24 cases of renal failure were diagnosed during the study on the basis of elevated serum blood nitrogen (BUN) and creatinine levels. On the day of admission, clinical hematology, serum biochemistry and urine analysis was carried out. The frequent hematological abnormalities observed in renal failure were non-regenerative normocytic normochromic anemia, neutrophilic leukocytosis with marked left shift, and toxic changes in neutrophils and their precursors. Serum chemistry indices like total serum protein, albumin and serum bilirubin remained unaltered. Alkaline phosphatase (ALP) values were higher than normal in 90% cases, whereas mean AST and ALT values were within normal range. The results of urinalysis revealed acidic urine, moderate to marked proteinuria and presence of blood.
Anemia, Hematology, Renal failure, Serum biochemistry
