1Department of Veterinary Gynaecology and Obstetrics, College of Veterinary and Animal Science, RAJUVAS, Bikaner, Rajasthan, India
3Department of Veterinary Clinical Complex, Sanskaram College of Veterinary and Animal Science, Jhajjar, Haryana, India
4Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Science, RAJUVAS, Bikaner, Rajasthan, India
5Department of Veterinary Pathology, College of Veterinary and Animal Science, RAJUVAS, Bikaner, Rajasthan, India
6Sneh Vet lab and Clinic Bhadra, Bhiwani, Haryana, India
*Corresponding author: satishnain26@gmail.com
Online Published on 14 September, 2022.
Successful management of parturition induction is a challenging task in canine. This study made to assess the efficacy of antiprogestagen mifepristone and prostaglandin misoprostol in induction of parturition in bitches. Total of 11 pregnant bitches with gestational age of more than 62 days confirmed by ultrasound scanning and not showing any sings of initiation of parturition were selected. Induction of parturition was initiated by mifepristone (3 mg/ kg b wt PO) twice a day or a combination of mifepristone (3 mg/ kg b wt PO) and misoprostol (200 µg for < 20 kg, 400 µg for > 20 kg b wt, i/vg) 12 h after second dose of mifepristone. The combination of both drugs mifepristone and misoprostol was more effective for parturition induction.
Mifeioristone, Misoprostol, Pregnancy termination
