Meta-Analysis: Hyperphosphatemia and Disequilibrium Syndrome in Renal Disease as Contributors to Mods Leading to Protein Restriction

Dialysis-related disequilibrium syndrome (DRDS) and hyperphosphatemia are frequent side effects in people with renal illness that can trigger systemic disorders such as Multiorgan Dysfunction Syndrome (MODS). to clarify the role that these variables play in MODS and how dietary protein restriction is affected. Results show that whereas DRDS causes neurological and metabolic abnormalities, hyperphosphatemia worsens vascular calcification and systemic inflammation. The danger of malnutrition exists even if protein limitation can lessen metabolic stress. A comprehensive approach that incorporates dialysis, medication, and nutrition is necessary to improve results.