Gurur Nanak Institute of Pharmaceutical Science and Technology, Kolkata, West Bengal, India
Online published on 19 February, 2018.
Recent discovery of CRISPR-Cas9 genome editing technique has opened up a new window for biotechnologists. The simplicity along with its accuracy and cost effectiveness has made the technique instant hit for modern day researchers. But the full potential of the technique is yet to be explored as there are some serious challenges and ethical issues needed to be addressed elaborately. In this article the development of CRISPR-Cas9 system has been described along with its special features, detailed discussion on the future directions and challenges has also been made.
Genome editing, CRISPR-Cas9, Nuclease, Human germline editing, Disease modeling, Ethical issues
