Docking Analysis of Tamilnadia uliginosa Retz. Rirveng & Sastre (Rubiaceae)

The development of a molecular docking tool usually starts with an efficient search algorithm, which places the ligand in the active site of the target protein in numerous different positions, orientations, and, in flexible docking, conformations. In the present study, fractionated methanolic extract was used for cytotoxic activity studies and found to be very effective. Detailed analysis of this fraction revealed that the major compound present in the fraction is quercetin, a flavanoid compound.