1Department of Diagnostic and Allied Health Sciences Faculty of Health and Life Sciences, Management & Science University, 40100, Shah Alam, Selangor, Malaysia
2Research Officer, Phytochemistry Program of Natural Products Division, Forest Research Institute, Malaysia
*Corresponding Author: Dr. Kue Chin Siang Senior Lecturer Faculty of Health and Life Sciences, Management & Science University, 40100, Shah Alam, Selangor, Malaysia. Email: cskue@msu.edu.mv, cskue3632@gmail.com
Online published on 5 October, 2018.
Kombucha mushroom tea is a fermented drink made with tea, sugar and yeast that known to possess various medicinal properties. This study was designed to evaluate the antioxidant and hepatoprotective effect of kombucha sweetener and its secondary metabolite on Sprague Dawley rats. AST and ALT level in secondary metabolites extracted from Kombucha sweeterner-and Kombucha sweetener-treated rats were significant lower compared to APAP treated group. The level of SOD, GPX and CAT were lowered compared to APAP treated group. Based on the findings, it can concluded that kombucha sweetener and its secondary metabolite has hepatoprotective activity against DILI.
Kombucha sweetener, drug-induced liver injury, hepatoprotective, acetaminophen, secondary metabolite
