International Journal of Medical Toxicology & Legal Medicine
  • Year: 2019
  • Volume: 22
  • Issue: 1and2

Effects of pesticide, indoxacarb on zebrafish (Danio Rerio) toxicity test

  • Author:
  • Subramanian Rammohan1,, Mariam Shahida Binti Saupi1, Syahida Ahmad2, Aniruddha Bhattacharjee1
  • Total Page Count: 3
  • Page Number: 162 to 164

1International Medical School, Management and Science University, Shah Alam, Selangor, Malaysia-40100

2Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia-43400, Serdang, Selangor, Malaysia

*Corresponding Author Subramanian Rammohan International Medical School, Management and Science University, Shah Alam, Selangor, Malaysia, 40100, Email: dr_subramaniam@msu.edu.my

Online published on 30 August, 2019.

Abstract

The effect of different concentrations of indoxacarb were studied on adult and embryos of zebrafish (Danio rerio). Acute and chronic toxicity tests were performed on adult and embryos, at different concentrations. At the highest concentration of 30 ppm, there was significant reduction on the hatching rate of embryos. The lethal concentration (LC50) in this study was 1.44 ppm. In acute and chronic toxicity on adult zebrafish, at concentrations of 0.5 ppm and 1.0 ppm, survival was until 14 days. Based on our findings we suggest to reduce the chemical footprint, if not on a total ban on indoxacarb, especially for agricultural applications.

Keywords

Pesticides, indoxacarb, toxicity, zebrafish