1Assistant Professor, Amity Institute of Forensic Sciences, Amity University Uttar Pradesh, Noida, India
2Assistant Professor, Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida, India
3Lecturer, Department of Chemistry, Lucknow Cristian Degree College, University of Lucknow, Lucknow, Uttar Pradesh, India
*Corresponding Author Dr. Amarnath Mishra Assistant Professor (Grade-III), Amity Institute of Forensic Sciences, Amity University, Noida, Uttar PradeshIndia Email: amishra5@amity.edu, drmishraa1@gmail.com
Online published on 21 March, 2022.
Insecticides are widely utilised and implicated in a number of severe and even deadly poisonings. The goal of this research was to come up with a better method for detecting malathion pesticide in urine and viscera samples. In all blank samples, the method's selectivity was acceptable, with negligible matrix influence. Three repetitions were done at varied concentrations to determine percent recovery. Malathion insecticide was shown to have a 92.4% recovery rate in biological matrices. The lowest concentration giving signal-to-noise ratios of at least 3:1 and 10:1, respectively, was defined as the limit of detection (LOD) and limit of quantification (LOQ). Malathion LODs and LOQs were determined to be 0.25 g/L and 0.75 g/L, respectively. The approach used in this study has been enhanced. Due to improved sensitivity, the amount of drug required has decreased. In forensic and analytical toxicology situations, the whole analytical methodology has grown more trustworthy, accurate, repeatable, and user-friendly.
Forensic toxicology, Insecticides, Liquid-liquid extraction, Gas chromatography-mass spectrometry
