Field experiments conducted during winter seasons of 1995–96 and 1996–97 revealed that metsulfuron-methyl @ 2 and 4 g/ha was effective in controlling Chenopodium album, Anagallis arvensis, Melitotus alba, Trifolium flagiferum, Medicago hispida, Vicia sativa and Cichorium intybus, but not Phalaris minor. The efficacy was improved with the addition of 2,4–0 @ 250 or 500 g/ha and isoproturon @ 500 g/ha. The efficacy of 2,4–0 at different rates was slightly of lower order. On the basis of two years' mean, higher grain yield of wheat was obtained with the application of metsulfuron-methyl @ 4 g/ha+2,4–0 @ 500 g/ha (5038 kg/ha) or metsulfuron-methyl @ 4 g/ha+2,4–0 @ 250 g/ha (4825 kg/ha) and hand weeding (4812 kg/ha) as against 3881 kg/ha under weedy control. However, the yield differences amongst metsulfuron-methyl @ 2 and 4 g/ha either alone or in mixed application with 2,4–0 were not significant.