Bio-efficacy of different herbicides in the first cutting of Japanese mint was studied during 1991 and 1992. Pre-emergence application of ethal fluralin at 0.3 and 0.4 kg, terbutryn at 0.50 and 0.75 kg, isoproturon 0.47 and 0.75 kg and isoproturon 0.37 kg plus pendimethalin 0.37 kg/ha provided effective control of weeds. Highest herb yield of 226 and 248 q/ha was recorded with pre-emergence application of ethal tluralin at 0.3 kg/ha during 1991 and isoproturon 0.47 kg/ha during 1992, respectively. On an average of two years, these treatments produced 15.8 and 13.2% more yield than two hand hoeings and 140.6 and 135.2% more than unweeded control, respectively.