Different tillage practices did not influence the population and dry maller of weeds and yield of wheat. Infestation of weeds caused 65% reduction in wheal grain yield. Post-emergence application of clodinafop at 0.06 kg ha−1 fb 2, 4-D at 0.50 kg ha−1 significantly reduced the population and dry matter of weeds and increased the grain yield of wheat. This combination proved more effcctive than isoproturon at 1.0 kg ha−1 + 2, 4-D at 0.50 kg ha−1.