Journal of Advances in Medicine
  • Year: 2013
  • Volume: 2
  • Issue: 2

Multimodal Analgesia Prolongs Duration of Postoperative Analgesia and Decreases Postoperative Pain Intensity in Short Surgical Procedures: a Randomized Controlled Trial.

  • Author:
  • Hazem E. Elsersy1,, Magdy Ch. Metyas2
  • Total Page Count: 10
  • Page Number: 57 to 66

1Anesthesia Department, Faculty of medicine, Menoufiya University, Shebin Elkom, Menoufiya, Egypt

2Lecturer, Anesthesia Faculty of Medicine, Ain Shams University. This Study was Funded by Menoufiya University Hospitals, Menoufiya, Egypt

*Corressponding Author: Hazem Elsersy, MD, lecturer of anesthesia, faculty of medicine, Menoufiya university. Email: hazelsersy@hotmail.com

Online published on 15 February, 2014.

Abstract

We examined the effect of preoperative combination of different analgesics and the role of each individual analgesic compared to control regarding postoperative pain

Patients were randomly allocated into either control; multiple treatment, perfalgan, opioid and voltaren group. The time for first request for analgesia and visual analogue score were compared by analysis of variance and tuckey Kramer test.

There was a main effect of treatment p>0.0001 in favor of multi-analgesia and opioid groups. Multi-analgesia group was better than opioid group p=0.016. There was a little improvement with paracetamol (perfalgan) but no effect of voltaren on duration of analgesia nevertheless;both have reduced VAS relative to control.

Combination ofnon-opioid analgesicsDiclofenac Na (voltaren), Paracetamol (perfalgan) with low dose morphine and dexamethasone have greatly prolonged duration of analgesia and reduced pain intensity without displaying notable side effects.

Keywords

Pain, postoperative, multimodal analgesia, analgesics nonopioid, diclofenac Na, analgesics non-opioid, paracetamol, analgesics opioid, morphine, dexamethasone