1Senior Resident, Department of General Medicine, ESI Post-Graduate Institute of Medical Science and Research, Maniktala, Kolkata, India
2Associate Professor, Department of Pharmacology, Burdwan Medical College, Burdwan, India
3Assistant Professor, Professor, Department of General Medicine, Burdwan Medical College, Burdwan, India
4Associate Professor, Anaestheisology, Bankura Sanmilani Medical College, Bankura, India
5Professor, General Medicine, Midnapore Medical College, Mednapore, India
*Corressponding Author: Email: pkmbmoh@gmail.com
Online published on 15 February, 2014.
Type 2 diabetes mellitus (T2DM) is a common metabolic disorder in India. It is recognised that the low testosterone level is associated with reduced insulin sensitivity and type 2 diabetes(T2DM)1. Testosterone level is comparatively lower in diabetic2–5. But data in this relation is lacking particulaly in rural india. So the aim of this study wastoevaluate the prevalence of hypogonadism among T2DM patients in rural India with an objective to assess and compare serum total Testosterone (TT), Folicle Stimulating Hormone(FSH) and Luteinizing Hormone(LH) level of male T2DM patients and age matched healthy control group.
It was an open label observational descriptive cross sectional study. Fifty male type 2 diabetic patients and 50 healthy control subjects were selected randomly following inclusion and exclusion criteria for this study. Blood sample was collected aseptically and properly for assessment TT, FSH, LH, and glycosylated haemoglobin.
Hypogonadism (TT<12nmol/l) was found in 68% of diabetic subjects and in 20% of healthy control group of those with diabetes 72.72% of diabetic whose serum TT level <12nmol/l had LH level<10nmol/l.
Testosterone levels were frequently low in men with T2DM compare to the healthy normal individuals of the same age group. Majority of them were suffering from hypogonadotrophichypogonadism (HH).
Type 2 DM, Serum Total Testosterone, LH, FSH, HH
