Journal of Medical Science & Research
  • Year: 2012
  • Volume: 3
  • Issue: 1

Regional Differences in Composition of Cholesterol Gallstones in India

  • Author:
  • Ashok M1, Arunkumar Krishnan2, G Choudhury3, Kalkura S Narayana4, V Jayanthi5
  • Total Page Count: 3
  • Page Number: 3 to 5

1Department of Physics, National Institute of Technology, Tiruchirappalli, Tamil Nadu, India

2Dept. of Gastroenterology and Hepatology, Stanley Medical College, Chennai, Tamil Nadu, India

3Dept. of Gastroenterology, SGPGI, Lucknow, Uttar Pradesh, India

4Crystal Growth Centre, Anna University, Chennai, Tamil Nadu, India

5Dept. of Gastroenterology and Hepatology, Stanley Medical College, Chennai, Tamil Nadu, India

Online published on 23 November, 2012.

Abstract

Regional differences in gallstone have been described in India. The elemental composition of gallstones from southern India has been reported. Cholesterol gallstones are rare in the southern parts of the Indian subcontinent.

was to determine any differences in the elemental composition of cholesterol gallstones from North and South India.

Fifteen samples of cholesterol gallstones from north and south India were subjected to Fourier Transform Infrared spectroscopy (FTIR) and Proton Induced X-ray Emission (PIXE).

FTIR showed the south Indian stones to be rich in cholesterol while the north Indian stones had in addition calcium carbonate, phosphate and palmitate. Concentrations of calcium, phosphorus and potassium were high in north Indian cholesterol gallstone while zinc, manganese, copper, chromium, iron and bromine were found in higher concentrations in south Indian cholesterol gallstone.

Distinct differences in elemental constituents have been observed in cholesterol gallstones from north and south India.

Keywords

gallstone, elemental constituents, PIXE, FTIR